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HLA graph, a free and ready-to-use bioinformatics tool to explore anti-HLA eplets reactivity pattern.

HLA - 1 Sept 2022

Usureau Cédric, Jacob Valentine, Dubois Valérie, Masson Dominique, Jollet Isabelle, Desoutter Judith, Taupin Jean-Luc, Guillaume Nicolas

Abstract excerpt

INTRODUCTION: HLA antigens are highly polymorphic, and their immunogenicity is dependent on the configurations of polymorphic amino acids. Monitoring anti-HLA immunization is essential in organ transplantation, as antibodies directed against HLA molecules are a major cause of rejection. Anti-HLA antibodies are not specific for HLA antigens, but recognize B-cell epitopes present on HLA molecules. METHODS: To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35672253
DOI: 10.1111/tan.14701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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