Article
Two sequence dimorphisms of DPB1 define the immunodominant serologic epitopes of HLA-DP.
Human immunology - 1 Oct 2009
Cano Pedro, Fernández-Viña Marcelo
Abstract excerpt
We describe two sets of epitopes present in HLA-DP molecules; they were identified with alloantibodies from clinical serum samples. Specificity was determined using fluorescent beads coated with single antigens and detected in a Luminex platform. Of the patients with anti-HLA class II antibodies, 18% had anti-DP antibodies; among these, 24 of 32 patients (75%) had antibodies against the dimorphic epitope sets...
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