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Using single antigen specificity magnetic beads for the isolation of specific antibodies against HLA antigens.

HLA - 1 Apr 2024

Vu Tri T M, Zhang Aiwen, Wang Ronald, Mathew Shalu, Abeywardana Tharindumala, Beltran-Lemus Marissa, Ma Vincent, Libby Mary, Thomas Dawn, Wakefield Ito, Zhu Quansheng, Lowe David, Pei Rui

Abstract excerpt

The presence of multiple donor-specific antibodies (DSAs) targeting HLA antigens poses a challenge to transplantation. Various techniques, including the use of recombinant cell lines and crossmatch cells have been developed to isolate DSAs. To simplify the extraction of HLA-specific DSAs from complex sera, we introduced magnetic beads with single HLA specificity (MagSort). Sera were treated with MagSort, allowing...

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Identifiers

PMID: 38634568
DOI: 10.1111/tan.15490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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