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Article

DNA mismatch repair defects: role in colorectal carcinogenesis.

Biochimie - 1 Jan 2002

Jacob Sandrine, Praz Françoise

Abstract excerpt

The inactivation of the DNA mismah repair (MMR) system, which is associated with the predisposition to the hereditary non-polyposis colorectal cancer (HNPCC), has also been documented in nearly 20% of the sporadic colorectal cancers. These tumors are characterized by a high frequency of microsate...

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Share to Adaptor Proteins, Signal Transducing
Share to Base Pair Mismatch
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11900875
DOI: 10.1016/s0300-9084(01)01362-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11900875-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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