Article
Association of IFIH1 and DDX58 genes polymorphism with susceptibility to COVID-19.
Medical microbiology and immunology - 1 Jun 2023
Feizollahi Parisa, Zamanian Mohammad Hossein, Falahi Sara, Salari Farhad, Mahmoudi Zahra, Faryadi Elham, Gorgin Karaji Ali, Rezaiemanesh Alireza
Abstract excerpt
Pattern recognition receptors of the innate immune system, such as RIG-I and MDA5, are responsible for recognizing viruses and inducing interferon production. Genetic polymorphisms in the coding regions of RLR may be associated with the severity of COVID-19. Considering the contribution of the RL...
Topics
- Humans
- Interferon-Induced Helicase, IFIH1
- DEAD-box RNA Helicases
- Genetic Predisposition to Disease
- COVID-19
- Genotype
- Polymorphism, Single Nucleotide
- DEAD Box Protein 58
- Receptors, Immunologic