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Article

Cup-like acute myeloid leukemia: new disease or artificial phenomenon?

Haematologica - 1 Feb 2008

Kroschinsky Frank P, Schäkel Ulrike, Fischer Rainer, Mohr Brigitte, Oelschlaegel Uta, Repp Roland, Schaich Markus, Soucek Silke, Baretton Gustavo, Ehninger Gerhard, Thiede Christian

Abstract excerpt

We investigated cup-like nuclear morphology of acute myeloid leukemia blasts in 266 randomly selected patients and its association with hematologic findings, disease markers and outcome data. Cup-like acute myeloid leukemia was diagnosed in 55 patients (21%). It was associated with female sex, high white blood cell and blast cell counts, normal karyotype, and low CD34 and HLA-DR expression. Mutations of FLT3,...

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Share to Antigens, CD34
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to fms-Like Tyrosine Kinase 3

Share to Gene Expression Regulation, Leukemic

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Source

Identifiers

PMID: 18223289
DOI: 10.3324/haematol.11669

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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