Article
Chronic myelomonocytic leukemia with NPM1 mutation or acute myeloid leukemia?
The oncologist - 6 Feb 2025
Castaño-Díez Sandra, Álamo José Ramón, López-Guerra Mònica, Gómez-Hernando Marta, Zugasti Inés, Jiménez-Vicente Carlos, Guijarro Francesca, López-Oreja Irene, Esteban Daniel, Charry Paola, Torrecillas Víctor, Mont-de Torres Lucia, Cortés-Bullich Albert, Bataller Álex, Guardia Ares, Munárriz Daniel, Carcelero Esther, Riu Gisela, Triguero Ana, Tovar Natalia, Vela Dolors, Beà Silvia, Costa Dolors, Colomer Dolors, Rozman Maria, Esteve Jordi, Díaz-Beyá Marina
Abstract excerpt
The 2022 WHO revision and the ICC classification have recently modified the diagnostic criteria for chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia. However, there is no consensus on whether CMML with NPM1 mutation (NPM1mut) should be diagnosed as AML. Nowadays, it is a subject of discussion because of its diagnostic and therapeutic implications. Therefore, we describe a case of a patient...
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