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Article

NASTRA: accurate analysis of short tandem repeat markers by nanopore sequencing with repeat-structure-aware algorithm.

Briefings in bioinformatics - 23 Sept 2024

Ren Zilin, Zhang Jiarong, Zhang Yixiang, Yang Tingting, Sun Pingping, Xue Jiguo, Bo Xiaochen, Zhou Bo, Yan Jiangwei, Ni Ming

Abstract excerpt

Short-tandem repeats (STRs) are the type of genetic markers extensively utilized in biomedical and forensic applications. Due to sequencing noise in nanopore sequencing, accurate analysis methods are lacking. We developed NASTRA, an innovative tool for Nanopore Autosomal Short Tandem Repeat Analysis, which overcomes traditional database-based methods' limitations and provides a precise germline analysis of STR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39322627
DOI: 10.1093/bib/bbae472
PMCID: PMC11424183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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