Article
Fourth-degree kinship analysis using 5198 single nucleotide polymorphisms detected by nanopore sequencing platform.
Forensic science international. Genetics - 1 Jun 2025
Zhang Jiarong, Yang Tingting, Shan Tiantian, Wei Yifan, Zhu Qiang, Zhang Ji, Yan Jiangwei
Abstract excerpt
Nanopore sequencing technology has high portability and affordability of devices, long sequencing reads, and GB-level data yields. In forensic applications, nanopore sequencing has been used in the identification of forensic short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs). Comparable to limited STRs, SNP markers have low per-locus discriminating power but are highly sufficient. Although...
Read the complete abstract on PubMedTopics
- Polymorphism, Single Nucleotide
- Humans
- Nanopore Sequencing
- Sequence Analysis, DNA
- Pedigree
- Linkage Disequilibrium
