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Nanopore sequencing of a forensic combined STR and SNP multiplex.

Forensic science international. Genetics - 1 Jan 2022

Tytgat Olivier, Škevin Sonja, Deforce Dieter, Van Nieuwerburgh Filip

Abstract excerpt

Nanopore sequencing for forensic purposes has gained attention, as it yields added discriminatory power compared to capillary electrophoresis (CE), without the need for a high up-front capital investment. Besides enabling the detection of iso-alleles, Massively Parallel Sequencing (MPS) facilitates the analysis of Short Tandem Repeats (STRs) and Single Nucleotide Polymorphisms (SNPs) in parallel. In this...

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PMID: 34742095
DOI: 10.1016/j.fsigen.2021.102621

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