Article
Human short tandem repeat identification using a nanopore-based DNA sequencer: a pilot study.
Journal of human genetics - 1 Jan 2020
Asogawa Minoru, Ohno Ayumu, Nakagawa So, Ochiai Eriko, Katahira Yasuhiro, Sudo Megumi, Osawa Motoki, Sugisawa Masatoshi, Imanishi Tadashi
Abstract excerpt
Short tandem repeats (STRs) are repetitive DNA sequences that are highly polymorphic and widely used for personal identification in the field of forensic medicine. The standard method for determining the repeat number of STRs is capillary electrophoresis of PCR products; however, the use of DNA sequencing has increased because it can identify same-sized alleles with nucleotide substitutions (iso-alleles). In this...
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