Article
Nanopore Sequencing of a Forensic STR Multiplex Reveals Loci Suitable for Single-Contributor STR Profiling.
Genes - 1 Apr 2020
Tytgat Olivier, Gansemans Yannick, Weymaere Jana, Rubben Kaat, Deforce Dieter, Van Nieuwerburgh Filip
Abstract excerpt
Nanopore sequencing for forensic short tandem repeats (STR) genotyping comes with the advantages associated with massively parallel sequencing (MPS) without the need for a high up-front device cost, but genotyping is inaccurate, partially due to the occurrence of homopolymers in STR loci. The goal of this study was to apply the latest progress in nanopore sequencing by Oxford Nanopore Technologies in the field of...
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