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Article

Low CD3 level is a risk factor for amyotrophic lateral sclerosis: a Mendelian randomization study.

Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 Feb 2025

Yang Wenzhi, Liu Xiangyi, Fan Dongsheng

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal disease characterized by neuronal degeneration of the spinal cord and brain and believed to be related to the immune system. In this study, our aim is to use Mendelian randomization (MR) to search for immune markers related to ALS. A total of 731 immune cell traits were included in this study. MR analysis was used to identify the causality between 731...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39316061
DOI: 10.1080/21678421.2024.2407408

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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