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Article

Circulating immune cells and risk of multiple sclerosis: A Mendelian randomization analysis.

Medicine - 9 Jan 2026

Zhou Heran, Yang Xuefei, Huang Ting

Abstract excerpt

Multiple sclerosis (MS) represents a significant global public health concern. Risk factors for MS include autoimmune diseases and immune cell dysfunctions. Immune cells, particularly T cells, B cells, and monocytes, play pivotal roles in the pathogenesis of MS. Nevertheless, the direct causal relationship between these immune cells and MS remains unclear. Genome-wide association studies (GWAS) and Mendelian...

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Identifiers

PMID: 41517661
DOI: 10.1097/MD.0000000000046954
PMCID: PMC12795000

Genes

CD27
CD28
CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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