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Circulating Levels of T-Cell Traits and the Risk of Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study.

Molecular neurobiology - 1 Dec 2024

Lu Ting, Luo Lijun, Yang Jie, Cheng Xiao, Sun Jingbo

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) represents a rare and potentially fatal neurodegenerative disease. Diverse T-cell subsets could potentially exert diametrically opposite impacts upon ALS development. A two-sample Mendelian randomization (MR) analysis was performed to investigate the correlation between 244 T-cell subsets and ALS risk. Genetic instrumental variables were procured from a standard genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38748065
DOI: 10.1007/s12035-024-04226-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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