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Article

HLA Genetic Diversity and Chronic Hepatitis B Virus Infection: Effect of Heterozygosity Advantage.

Medical sciences (Basel, Switzerland) - 29 Aug 2024

Tălăngescu Adriana, Tizu Maria, Calenic Bogdan, Mihăilescu Dan Florin, Constantinescu Alexandra Elena, Constantinescu Ileana

Abstract excerpt

This research aims to determine whether HLA heterozygosity confers a protective effect against hepatitis B virus infection by analyzing the relationship between HLA diversity and the risk of hepatitis B virus (HBV) infection. A total of 327 hepatitis B patients were selected and categorized based on their clinical status: 284 patients with chronic HBV infection and 43 patients with HBV-related liver cirrhosis...

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Source

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Identifiers

PMID: 39311157
DOI: 10.3390/medsci12030044
PMCID: PMC11417839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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