Article
HLA-DQA1 & DQB1 variants associated with hepatitis B virus-related chronic hepatitis, cirrhosis & hepatocellular carcinoma.
The Indian journal of medical research - 1 Jun 2018
Karra Vijay Kumar, Chowdhury Soumya Jyoti, Ruttala Rajesh, Gumma Phani Kumar, Polipalli Sunil Kumar, Chakravarti Anita, Kar Premashis
Abstract excerpt
Background & objectives: Clinical outcome after hepatitis B virus (HBV) exposure varies extremely from spontaneous clearance to chronic hepatitis B and often progresses to liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Host genetic factor plays an important role in the regulation of immune response. This study was aimed to investigate whether HLA class II DQA1 and DQB1 gene polymorphism were associated...
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