Article
Predicting Lung Cancer in Korean Never-Smokers With Polygenic Risk Scores.
Genetic epidemiology - 1 Jan 2025
Kim Juyeon, Park Young Sik, Kim Jin Hee, Hong Yun-Chul, Kim Young-Chul, Oh In-Jae, Jee Sun Ha, Ahn Myung-Ju, Kim Jong-Won, Yim Jae-Joon, Won Sungho
Abstract excerpt
In the last few decades, genome-wide association studies (GWAS) with more than 10,000 subjects have identified several loci associated with lung cancer and these loci have been used to develop novel risk prediction tools for cancer. The present study aimed to establish a lung cancer prediction model for Korean never-smokers using polygenic risk scores (PRSs); PRSs were calculated using a...
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