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Article

BRAF mutations and the association of V600E with CD133 and CDX2 expression in a Pakistani colorectal carcinoma cohort.

BMC cancer - 19 Sept 2024

Hassan Sobia, Mirza Talat, Khatoon Ambrina, Bukhari Uzma, Shaikh Fouzia, Karim Asad

Abstract excerpt

BACKGROUND: Despite a high incidence of colorectal carcinoma, data regarding genetic aberrations in colorectal carcinoma (CRC) patients in Pakistan is scarce. This study aimed to determine the frequency of BRAFV600E mutations in colorectal carcinoma tissue in the Pakistani population and to assoc...

Topics

Humans
Proto-Oncogene Proteins B-raf
CDX2 Transcription Factor
Colorectal Neoplasms
AC133 Antigen
Male
Female
Middle Aged
Mutation
Adult
Pakistan
Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Biomarkers, Tumor

Cohort Studies

Immunohistochemistry

Aged, 80 and over

Source

Open in PubMed Open full text

Identifiers

PMID: 39300378
DOI: 10.1186/s12885-024-12925-z
PMCID: PMC11411998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-39300378-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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