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Article

Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population.

BMC medical genetics - 7 Nov 2019

Razak Suhail, Bibi Nousheen, Dar Javid Ahmad, Afsar Tayyaba, Almajwal Ali, Parveen Zahida, Jahan Sarwat

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is categorized by alteration of vital pathways such as β-catenin (CTNNB1) mutations, WNT signaling activation, tumor protein 53 (TP53) inactivation, BRAF, Adenomatous polyposis coli (APC) inactivation, KRAS, dysregulation of epithelial to mesenchymal transition (EMT) genes, MYC amplification, etc. In the present study an attempt was made to screen CTNNB1 gene in colorectal...

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Identifiers

PMID: 31699039
DOI: 10.1186/s12881-019-0911-y
PMCID: PMC6836551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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