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Clinical features and mutation analysis of class 1/2/3 BRAF mutation colorectal cancer.

Chinese clinical oncology - 1 Feb 2024

Huang Yingying, Jia Wenzhuo, Zhao Gang, Zhao Yunbo, Zhang Shuai, Li Zhongkang, Wu Guoju

Abstract excerpt

BACKGROUND: BRAF (B-Raf proto-oncogene, serine/threonine kinase)-mutated colorectal cancer (CRC) still has poor prognostic. The efficacy of BRAF inhibitor is unpredictable just that intrinsic genetic complexity, immune microenvironment and partially unknown reason. Understanding the co-mutation mechanism can help improve treatment and follow-up strategies. METHODS: We retrospectively analyzed 35...

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PMID: 38372057
DOI: 10.21037/cco-23-117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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