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Article

Cognitive behavioral phenotyping of DSCAM heterozygosity as a model for autism spectrum disorder.

Genes, brain, and behavior - 1 Oct 2024

Neff Ryan C, Stangis Katherine A, Beniwal Ujjawal, Hergenreder Ty, Ye Bing, Murphy Geoffrey G

Abstract excerpt

It is estimated that 1 in 36 children are affected by autism spectrum disorder (ASD) in the United States, which is nearly a twofold increase from a decade ago. Recent genetic studies have identified de novo loss-of-function (dnLoF) mutations in the Down Syndrome Cell Adhesion Molecule (DSCAM) as a strong risk factor for ASD. Previous research has shown that DSCAM ablation confers social interaction deficits and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39294095
DOI: 10.1111/gbb.70002
PMCID: PMC11410459

Genes

DSCAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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