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Loss of the intellectual disability and autism gene <i>Cc2d1a</i> and its homolog <i>Cc2d1b</i> differentially affect spatial memory, anxiety, and hyperactivity

2017-11-21

Abstract excerpt

<h4>ABSTRACT</h4> Hundreds of genes are mutated in non-syndromic intellectual disability (ID) and autism spectrum disorder (ASD), with each gene often involved in only a handful of cases. Such heterogeneity can be daunting, but rare recessive loss of function (LOF) mutations can be a good starting point to provide insight into the mechanisms of neurodevelopmental disease. Biallelic LOF mutations in the signaling...

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Literature Corpus work
abcc6bdd-1ead-5987-985d-73a78531b9cc
DOI
10.1101/222638
Open publication

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Loss of the intellectual disability and autism gene <i>Cc2d1a</i> and its homolog <i>Cc2d1b</i> differentially affect spatial memory, anxiety, and hyperactivityDOI 10.1101/222638
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