Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leptin receptor is a key gene involved in the immunopathogenesis of thyroid‐associated ophthalmopathy

14 May 2021

Abstract excerpt

Thyroid-associated ophthalmopathy (TAO), the most common and severe manifestation of Graves' disease (GD), is a disfiguring and potentially blinding autoimmune disease. The high relapse rate (up to 20%) and substantial side effects of glucocorticoid treatment further decrease the life quality of TAO patients. To develop novel therapies, we amid to explore the immunopathogenesis of TAO. To identify the key...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clusterin in disease pathology
Share to Thyroid Cancer Diagnosis and Treatment
Share to Thyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33988300
DOI: 10.1111/jcmm.16605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leptin receptor is a key gene involved in the immunopathogenesis of thyroid‐associated ophthalmopathyPMID 33988300Read ↗

Mechanisms of immune-related differentially expressed genes in thyroid-associated ophthalmopathy based on the GEO databaseSemantic proximity Read ↗

Deciphering the LncRNA-Mediated Gene Regulatory Network and Pathogenic Cascades in Thyroid-Associated OphthalmopathySemantic proximity Read ↗

Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.Semantic proximity Read ↗

Integrative transcriptomic profiling and machine learning reveal hypoxia-associated molecular signatures for precision diagnosis in thyroid eye diseaseSemantic proximity Read ↗

Research progress on the pathogenesis of Graves’ ophthalmopathy: Based on immunity, noncoding RNA and exosomesSemantic proximity Read ↗

Exploring Prognostic Gene Expression Signature for Thyroid Eye DiseaseSemantic proximity Read ↗

Unravelling the pathogenic mechanisms in Graves’ orbitopathySemantic proximity Read ↗

IL-17 and IL-38 gene polymorphisms in thyroid-associated ophthalmopathy.Semantic proximity Read ↗

Identification and validation of ferroptosis-related genes and immune cell infiltration in thyroid associated ophthalmopathySemantic proximity Read ↗

Dynamic transition of Tregs to cytotoxic phenotype amid systemic inflammation in Graves' ophthalmopathy.Semantic proximity Read ↗

Transcriptomic profiling of thyroid eye disease orbital fat demonstrates differences in adipogenicity and IGF-1R pathwaySemantic proximity Read ↗

Novel insights into the pathogenesis of thyroid eye disease through ferroptosis-related gene signature and immune infiltration analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.