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Mitochondrial sequence variants: testing imputation accuracy and their association with dairy cattle milk traits.

Genetics, selection, evolution : GSE - 12 Sept 2024

Dorji Jigme, Chamberlain Amanda J, Reich Coralie M, VanderJagt Christy J, Nguyen Tuan V, Daetwyler Hans D, MacLeod Iona M

Abstract excerpt

BACKGROUND: Mitochondrial genomes differ from the nuclear genome and in humans it is known that mitochondrial variants contribute to genetic disorders. Prior to genomics, some livestock studies assessed the role of the mitochondrial genome but these were limited and inconclusive. Modern genome sequencing provides an opportunity to re-evaluate the potential impact of mitochondrial variation on livestock traits....

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PMID: 39266998
DOI: 10.1186/s12711-024-00931-5
PMCID: PMC11391750

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