Article
Strategies for imputation to whole genome sequence using a single or multi-breed reference population in cattle.
BMC genomics - 27 Aug 2014
Brøndum Rasmus Froberg, Guldbrandtsen Bernt, Sahana Goutam, Lund Mogens Sandø, Su Guosheng
Abstract excerpt
BACKGROUND: The advent of low cost next generation sequencing has made it possible to sequence a large number of dairy and beef bulls which can be used as a reference for imputation of whole genome sequence data. The aim of this study was to investigate the accuracy and speed of imputation from a high density SNP marker panel to whole genome sequence level. Data contained 132 Holstein, 42 Jersey, 52 Nordic Red...
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