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Article

Polymorphisms in genes involved in regulating follicular helper T cell differentiation predict de novo donor-specific antibody formation after liver transplantation.

Human immunology - 1 Nov 2024

Ono Kosuke, Ide Kentaro, Nakano Ryosuke, Sakai Hiroshi, Shimizu Seiichi, Tahara Hiroyuki, Ohira Masahiro, Tanaka Yuka, Ohdan Hideki

Abstract excerpt

BACKGROUND: De novo donor-specific antibodies (dnDSAs) significantly affect the long-term outcomes of liver transplantation (LT), highlighting the importance of risk prediction. Follicular helper T (Tfh) cells have been implicated in dnDSA formation after transplantation. Considering the influence of immune response gene polymorphisms on transplantation outcomes, we investigated the association between...

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PMID: 39255558
DOI: 10.1016/j.humimm.2024.111103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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