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Article

Integrative Genomic and Single-Cell Insights Into Efferocytosis-Mediated Immune Regulation in Clear Cell Renal Cell Carcinoma.

Mediators of inflammation - 1 Jan 2025

Shi Bing, Deng Minghao, Ma Jiakang, Chen Chao, Peng Aijin, Zhu Anli, Yang Rongchao, Jin Zhenhua, Zhu Jian, Zhang Mingcong, Shen Shuijie

Abstract excerpt

Background: Efferocytosis, the phagocytic clearance of apoptotic cells, plays a key role in tumor progression and immune regulation, but its prognostic significance and molecular mechanisms in clear cell renal cell carcinoma (ccRCC) remain unclear. Methods: Four efferocytosis-related pathways were curated, and the pathway activities were quantified in ccRCC. Prognostic genes were identified by univariate Cox...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41498044
DOI: 10.1155/mi/8710699
PMCID: PMC12767426

Genes

RAC1

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