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Article

Effect of hypoxia on HIF-1α and NOS3 expressions in CD34+ cells of JAK2V617F-positive myeloproliferative neoplasms.

Advances in medical sciences - 1 Sept 2023

Şoroğlu Can Veysel, Uslu-Bıçak İldeniz, Toprak Selin Fulya, Yavuz Akif Selim, Sözer Selçuk

Abstract excerpt

PURPOSE: Myeloproliferative neoplasms (MPN) are a heterogeneous group of hematopoietic stem-cell diseases with excessive proliferation of one or more blood cell lines. In this study, we evaluated the effect of different oxygen concentrations on HIF-1α and NOS3 gene expression to determine the effect of the bone marrow microenvironment on JAK2V617F positive Philadelphia chromosome negative (Ph-) MPNs. PATIENTS AND...

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Share to Antigens, CD34
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nitric Oxide Synthase Type III

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Identifiers

PMID: 37075583
DOI: 10.1016/j.advms.2023.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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