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Genomic Profiling and Immune Phenotyping of Neuroendocrine Bladder Cancer

3 Sept 2024

Abstract excerpt

PURPOSE: Neuroendocrine bladder cancer (NEBC) poses a formidable clinical challenge and attracts keen interests to explore immunotherapy as a viable treatment option. However, a comprehensive immunogenomic landscape has yet to be thoroughly investigated. EXPERIMENTAL DESIGN: Leveraging a long-term cohort of natural NEBC cases, we employed a multimodal approach integrating genomic (n = 19), transcriptomic (n = 3),...

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PMID: 39226396
DOI: 10.1158/1078-0432.ccr-24-1277

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