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Article

Comprehensive genomic profiling of neuroendocrine bladder cancer pinpoints molecular origin and potential therapeutics.

Oncogene - 1 May 2018

Shen Peiye, Jing Ying, Zhang Ruiyun, Cai Mei-Chun, Ma Pengfei, Chen Haige, Zhuang Guanglei

Abstract excerpt

Neuroendocrine bladder cancer is a relatively rare but often lethal malignancy, with cell of origin, oncogenomic architecture and standard treatment poorly defined. Here we performed comprehensive whole-genome and transcriptome sequencing on a unique cohort of genitourinary neuroendocrine neoplasms, mainly small cell carcinomas of the urinary bladder. The mutational landscape and signatures of neuroendocrine...

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Source

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PMID: 29535424
DOI: 10.1038/s41388-018-0192-5

Genes

ERBB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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