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Article

Histopathologic, Molecular, and Clinical Profiling of Lymphoepithelioma-like Carcinoma of the Bladder.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2024

Koll Florestan Johannes, Weers Lillian, Weigert Andreas, Banek Severine, Köllermann Jens, Kluth Luis, Wenzel Mike, Garcia Cristina Cano, Szarvas Tibor, Wessolly Michael, Ingenwerth Marc, Jeroch Jan, Döring Claudia, Chun Felix K-H, Wild Peter J, Reis Henning

Abstract excerpt

Lymphoepithelioma-like carcinoma of the bladder (LELC-B) is a rare histologic subtype characterized by strong immune cell (IC) infiltrates. A better prognosis and favorable response rates to immune checkpoint inhibitors have been described. We aimed to characterize the molecular profiles and IC infiltration of LELC-B for a better understanding of its therapeutic implications. We identified 11 muscle-invasive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39097190
DOI: 10.1016/j.modpat.2024.100588

Genes

CD163
CD4

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