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Article

Decreased dopachrome oxidoreductase activity in yellow mice.

The Journal of heredity - 1 Jan 2000

Barber J I, Townsend D, Olds D P, King R A

Abstract excerpt

Dopachrome oxidoreductase (DCOR) is a newly characterized enzyme in the melanin synthetic pathway, active in the conversion of dopachrome to 5,6-dihydroxyindole. DCOR and tyrosinase activity were measured in skin anagen hairbulbs from lethal yellow (Ay/a), sienna yellow (Asy/a) and recessive yellow (e/e) mice with and without treatment with melanocyte-stimulating hormone (MSH). DCOR activity was low (Asy/a) or...

Topics

Animals
Catechol Oxidase
Intramolecular Oxidoreductases
Melanocyte-Stimulating Hormones
Melanocytes
Mice
Mice, Inbred C57BL
Monophenol Monooxygenase
Mutation
Pigmentation Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 3920305
DOI: 10.1093/oxfordjournals.jhered.a110019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3920305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Decreased dopachrome oxidoreductase activity in yellow mice.PMID 3920305Read ↗

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