Article
Decreased dopachrome oxidoreductase activity in yellow mice.
The Journal of heredity - 1 Jan 2000
Barber J I, Townsend D, Olds D P, King R A
Abstract excerpt
Dopachrome oxidoreductase (DCOR) is a newly characterized enzyme in the melanin synthetic pathway, active in the conversion of dopachrome to 5,6-dihydroxyindole. DCOR and tyrosinase activity were measured in skin anagen hairbulbs from lethal yellow (Ay/a), sienna yellow (Asy/a) and recessive yellow (e/e) mice with and without treatment with melanocyte-stimulating hormone (MSH). DCOR activity was low (Asy/a) or...
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