Agouti alleles influence thiol concentrations in hair follicles and extrafollicular tissues of mice (Ay/a, AwJ/AwJ, a/a).

doi:10.1111/j.1600-0749.1995.tb00678.x

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Article

Agouti alleles influence thiol concentrations in hair follicles and extrafollicular tissues of mice (Ay/a, AwJ/AwJ, a/a).

Pigment cell research - 1 Dec 1995

Granholm D E, Reese R N, Granholm N H

Abstract excerpt

Agouti protein (AP) expression in the wild-type agouti mouse (AwJ/AwJ) coincides with a switch in hair follicle melanogenesis from black (eumelanin) to yellow (pheomelanin). Ectopic overexpression of AP in the lethal yellow (Ay/a) mouse cause a pure yellow coat and the lethal yellow syndrome. Thi...

Topics

Adipose Tissue
Agouti Signaling Protein
Alleles
Animals
Cysteine
Female
Glutathione
Glutathione Reductase
Hair
Hair Follicle
Intercellular Signaling Peptides and Proteins
Liver
Mice
Mice, Inbred C57BL
Proteins
Skin Pigmentation
Spleen

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