Article
Tyrosinase activity (TH, DO, PAGE-defined isozymes) and melanin production in regenerating hairbulb melanocytes of lethal yellow (Ay/a), black (a/a), agouti (AwJ/AwJ/) and albino (a/a/c2J/c2J) mice (C57BL/6J).
Pigment cell research - 1 Nov 1990
Granholm N H, Opbroek A J, Harvison G A, Kappenman K E
Abstract excerpt
We compared tyrosinase activity (TH, DO, and native PAGE-defined isozymes) and melanin production in particulate and soluble fractions of hairbulb melanocytes of lethal yellow (Ay/a C/C), nonagouti black (a/a C/C), and albino (a/a c2J/c2J) of 3-, 6-, 9-, and 12-day regenerating hairbulbs. With respect to tyrosine hydroxylase (TH) and dopa oxidase (DO) activities, Ay/a melanocytes possessed only 25-35% of the...
Topics
- Animals
- Dihydroxyphenylalanine
- Electrophoresis, Polyacrylamide Gel
- Genotype
- Hair
- Isoenzymes
- Kinetics
- Melanins
- Melanocytes
- Mice
- Mice, Inbred C57BL