Article
The eumelanin and pheomelanin contents in dorsal hairs of female recessive yellow mice are greater than in male.
Journal of dermatological science - 1 Jan 2007
Hirobe Tomohisa, Wakamatsu Kazumasa, Ito Shosuke
Abstract excerpt
BACKGROUND: The murine recessive yellow (Mc1r(e)) is a loss-of-function mutation in the receptor for alpha-melanocyte-stimulating hormone (MSH), melanocortin receptor 1 (MC1R), and produces yellow coats by inducing pheomelanin synthesis in hair follicular melanocytes. OBJECTIVE: It is not known whether the Mc1r(e) mutation affects pheomelanin synthesis in other skin sites. In this study, the eumelanin and...
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