Article
Estrogen increases hair pigmentation in female recessive yellow mice.
Zoological science - 1 Jun 2010
Hirobe Tomohisa, Kiuchi Megumi, Wakamatsu Kazumasa, Ito Shosuke
Abstract excerpt
Murine recessive yellow (Mc1r(e)) is a loss-of-function mutation in the receptor for alpha-melanocyte-stimulating hormone, melanocortin receptor 1 (Mc1r), and results in a yellow coat by inducing pheomelanin synthesis in hair follicular melanocytes. We previously showed that eumelanin and pheomelanin content in dorsal hair in female Mc1r(e)/Mc1r(e) mice 5 weeks after birth was greater than that in male mice. To...
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