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Article

Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume.

PloS one - 1 Jan 2024

Uchimura Yasuhiro, Hino Kodai, Hattori Kosuke, Kubo Yoshinori, Owada Airi, Kimura Tomoko, Sugawara Lucia, Kume Shinji, Bellier Jean-Pierre, Yanagisawa Daijiro, Shiino Akihiko, Nakayama Takahisa, Daigo Yataro, Mashimo Tomoji, Udagawa Jun

Abstract excerpt

Epidemiological studies suggest that poor nutrition during pregnancy predisposes offspring to the development of lifestyle-related noncommunicable diseases and psychiatric disorders later in life. However, the molecular mechanisms underlying this predisposition are not well understood. In our previous study, using rats as model animals, we showed that behavioral impairments are induced by prenatal undernutrition....

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PMID: 39197039
DOI: 10.1371/journal.pone.0309461
PMCID: PMC11356391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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