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Identification of the molecular link: STAT3 is a shared key gene linking postmenopausal osteoporosis and sarcopenia

28 Aug 2024

Abstract excerpt

Aims This study explored the shared genetic traits and molecular interactions between postmenopausal osteoporosis (POMP) and sarcopenia, both of which substantially degrade elderly health and quality of life. We hypothesized that these motor system diseases overlap in pathophysiology and regulatory mechanisms. Methods We analyzed microarray data from the Gene Expression Omnibus (GEO) database using weighted gene...

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PMID: 39195444
DOI: 10.1302/2046-3758.138.bjr-2023-0351.r2

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