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Article

Investigating potential novel therapeutic targets and biomarkers for ankylosing spondylitis using plasma protein screening.

Frontiers in immunology - 1 Jan 2024

You Wenkang, Lin Yanbin, Liu Mingzhong, Lin Zhangdian, Ye Rongjie, Zhang Canhong, Zeng Rongdong

Abstract excerpt

Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting the spine and sacroiliac joints. Recent genetic studies suggest certain plasma proteins may play a causal role in AS development. This study aims to identify and characterize these proteins using Mendelian randomization (MR) and colocalization analyses. Methods: Plasma protein data were obtained from recent publications in Nature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39185422
DOI: 10.3389/fimmu.2024.1406041
PMCID: PMC11341372

Genes

IL23R
IL7R
TYMP
CCL8
ERAP1
IL12B
IL18R1
TNFAIP6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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