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Article

GWASBrewer: An R Package for Simulating Realistic GWAS Summary Statistics.

Genetic epidemiology - 1 Jan 2025

Morrison Jean

Abstract excerpt

Many statistical genetics analysis methods make use of GWAS summary statistics. Best statistical practice requires evaluating these methods in realistic simulation experiments. However, simulating summary statistics by first simulating individual genotype and phenotype data is extremely computationally demanding. This high cost may force researchers to conduct overly simplistic simulations that fail to accurately...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39370594
DOI: 10.1002/gepi.22594
PMCID: PMC11656154

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