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Article

A whole-genome simulator capable of modeling high-order epistasis for complex disease.

Genetic epidemiology - 1 Nov 2013

Yang Wei, Gu C Charles

Abstract excerpt

Genome-wide association studies (GWAS) have been successful in finding numerous new risk variants for complex diseases, but the results almost exclusively rely on single-marker scans. Methods that can analyze joint effects of many variants in GWAS data are still being developed and trialed. To evaluate the performance of such methods it is essential to have a GWAS data simulator that can rapidly simulate a large...

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Identifiers

PMID: 24114848
DOI: 10.1002/gepi.21761
PMCID: PMC4143152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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