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Article

Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping.

Nature communications - 22 Aug 2024

Ector Carolin, Schmal Christoph, Didier Jeff, De Landtsheer Sébastien, Finger Anna-Marie, Müller-Marquardt Francesca, Schulte Johannes H, Sauter Thomas, Keilholz Ulrich, Herzel Hanspeter, Kramer Achim, Granada Adrián E

Abstract excerpt

The circadian clock, a fundamental biological regulator, governs essential cellular processes in health and disease. Circadian-based therapeutic strategies are increasingly gaining recognition as promising avenues. Aligning drug administration with the circadian rhythm can enhance treatment efficacy and minimize side effects. Yet, uncovering the optimal treatment timings remains challenging, limiting their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39169017
DOI: 10.1038/s41467-024-51611-3
PMCID: PMC11339390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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