Article

Time series-free rhythm profiling using COFE reveals multi-omic circadian rhythms in in-vivo human cancers

2024-03-15

Abstract excerpt

The study of the ubiquitous circadian rhythms in human physiology typically requires regular measurements across time. Repeated sampling of the different internal tissues that house circadian clocks is both practically and ethically infeasible. Here, we present a novel unsupervised machine learning approach (COFE) that can use single high-throughput (omics) samples from individuals to reconstruct circadian rhythms...

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Literature Corpus work: a0052532-c915-56d2-997f-ae56a8d92698
DOI: 10.1101/2024.03.13.584582

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