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Article

Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c.

Neuron - 15 Jul 2015

Wiegreffe Christoph, Simon Ruth, Peschkes Katharina, Kling Carolin, Strehle Michael, Cheng Jin, Srivatsa Swathi, Liu Pentao, Jenkins Nancy A, Copeland Neal G, Tarabykin Victor, Britsch Stefan

Abstract excerpt

During neocortical development, neurons undergo polarization, oriented migration, and layer-type-specific differentiation. The transcriptional programs underlying these processes are not completely understood. Here, we show that the transcription factor Bcl11a regulates polarity and migration of upper layer neurons. Bcl11a-deficient late-born neurons fail to correctly switch from multipolar to bipolar morphology,...

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PMID: 26182416
DOI: 10.1016/j.neuron.2015.06.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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