Landscapes of HLA Mismatching in Contemporary Unrelated Haematopoietic Cell Transplantation.

doi:10.1111/tan.70637

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Article

Landscapes of HLA Mismatching in Contemporary Unrelated Haematopoietic Cell Transplantation.

HLA - 1 Mar 2026

Arrieta-Bolaños Esteban, Bonneville Edouard F, Crivello Pietro, Gedde-Dahl Tobias, Peffault de Latour Régis, Salmenniemi Urpu, Kröger Nicolaus, Yakoub-Agha Ibrahim, Zecca Marco, Choi Goda, Crawley Charles, Tholouli Eleni, Dubois Valérie, Peräsaari Juha, Wieten Lotte, Marsh Steven G E, Bengtsson Mats, Hoogenboom Jorinde D, Kuball Jürgen, Malard Florent, Ruggeri Annalisa, Fleischhauer Katharina

Abstract excerpt

Haematopoietic cell transplantation (HCT) with HLA-mismatched unrelated donors (MMUD) offers access to curative therapy for patients lacking well-matched donors. Accumulating evidence suggests that functional matching among allele-mismatched pairs can significantly influence patient outcomes. Therefore, real-world data on mismatch frequencies in MMUD-HCT could provide fundamental information for the assessment of...

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PMID: 41811229
DOI: 10.1111/tan.70637
PMCID: PMC12978212

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