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Article

Finemap-MiXeR: A variational Bayesian approach for genetic finemapping.

PLoS genetics - 1 Aug 2024

Akdeniz Bayram Cevdet, Frei Oleksandr, Shadrin Alexey, Vetrov Dmitry, Kropotov Dmitry, Hovig Eivind, Andreassen Ole A, Dale Anders M

Abstract excerpt

Genome-wide association studies (GWAS) implicate broad genomic loci containing clusters of highly correlated genetic variants. Finemapping techniques can select and prioritize variants within each GWAS locus which are more likely to have a functional influence on the trait. Here, we present a novel method, Finemap-MiXeR, for finemapping causal variants from GWAS summary statistics, controlling for correlation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39146375
DOI: 10.1371/journal.pgen.1011372
PMCID: PMC11349196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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