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Article

The flashfm approach for fine-mapping multiple quantitative traits.

Nature communications - 22 Oct 2021

Hernández N, Soenksen J, Newcombe P, Sandhu M, Barroso I, Wallace C, Asimit J L

Abstract excerpt

Joint fine-mapping that leverages information between quantitative traits could improve accuracy and resolution over single-trait fine-mapping. Using summary statistics, flashfm (flexible and shared information fine-mapping) fine-maps signals for multiple traits, allowing for missing trait measurements and use of related individuals. In a Bayesian framework, prior model probabilities are formulated to favour...

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Identifiers

PMID: 34686674
DOI: 10.1038/s41467-021-26364-y
PMCID: PMC8536717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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