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Article

Evaluating the causal connections between sleep duration and disease prevalence: A comprehensive systematic review and meta-analysis of Mendelian randomization studies.

Medicine - 9 Jan 2026

Wang Zhihui, Yao Lingyu, Tu Mengyue

Abstract excerpt

BACKGROUND: The causal link between sleep duration and diverse health conditions remains unconfirmed. This meta-analysis aimed to clarify these relationships by synthesizing Mendelian randomization (MR) study evidence. METHODS: PubMed was systematically searched up to February 15, 2024, for MR studies exploring genetic predispositions to sleep duration/insomnia (short/long/overall sleep duration, insomnia) and...

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Identifiers

PMID: 41517697
DOI: 10.1097/MD.0000000000045225
PMCID: PMC12795056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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