Article
Causal effects of sleep traits on metabolic syndrome and its components: a Mendelian randomization study.
Sleep & breathing = Schlaf & Atmung - 1 Jun 2024
Yang Yongli, Wen Long, Shi Xuezhong, Yang Chaojun, Fan Jingwen, Zhang Yi, Shen Guibin, Zhou Huiping, Jia Xiaocan
Abstract excerpt
PURPOSE: Previous observational studies have suggested an association between sleep disturbance and metabolic syndrome (MetS). However, it remains unclear whether this association is causal. This study aims to investigate the causal effects of sleep-related traits on MetS using Mendelian randomization (MR). METHODS: Single-nucleotide polymorphisms strongly associated with daytime napping, insomnia, chronotype,...
Topics
- Humans
- Metabolic Syndrome
- Mendelian Randomization Analysis
- Polymorphism, Single Nucleotide
- Genome-Wide Association Study
- Sleep
- Sleep Initiation and Maintenance Disorders
- Male
- Sleep Wake Disorders
- Female